Spontaneous Clearance of Mycobacterium ulcerans in a Case of Buruli Ulcer

نویسندگان

  • Claire L. Gordon
  • John A. Buntine
  • John A. Hayman
  • Caroline J. Lavender
  • Janet A. Fyfe
  • Patrick Hosking
  • Paul D. R. Johnson
چکیده

1 Department of Infectious Diseases, Austin Health, Melbourne, Australia, 2 Department of Surgery, Box Hill Hospital, Melbourne, Australia, 3 Department of Surgery, Monash University, Melbourne, Australia, 4 Department of Anatomy and Developmental Biology, Monash University, Melbourne, Australia, 5 WHO Collaborating Centre for Mycobacterium ulcerans (Western Pacific Region) and Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia, 6 Department of Pathology, Box Hill Hospital, Melbourne, Australia

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Draft Genome Sequence of Mycobacterium ulcerans S4018 Isolated from a Patient with an Active Buruli Ulcer in Benin, Africa

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Detection of Mycobacterium ulcerans by real-time PCR with improved primers

BACKGROUND Buruli ulcer is a severe skin disease caused by Mycobacterium ulcerans. Real-time PCR targeting the IS2404 sequence has been used as a reliable and rapid method for the diagnosis of Buruli ulcer and detection of M. ulcerans in the environment. The genome of M. ulcerans contains hundreds of IS2404 copies, which have variability in certain sequences. Therefore, the design of new primer...

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1. Asiedu K, Sherpbier R, Raviglione MC. Buruli ulcer: Mycobacterium ulcerans infection. Geneva: World Health Organization; 2000. 2. Marion E, Eyangoh S, Yeramian E, Doannio J, Landier J, Aubry J, et al. Seasonal and regional dynamics of M. ulcerans transmission in environmental context: deciphering the role of water bugs as hosts and vectors. PLoS Negl Trop Dis. 2010;4:e731. DOI: 10.1371/journ...

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2011